Supplements for IBD: Fish Oil

• Fish oil:
  • Quality matters
    • You want it to be enteric coated so that it resists stomach acid breakdown, gets further down into the GI tract
    • Is well-sourced
    • Has been tested for environmental toxins 
  • Dosing matters:
    • 2-3 g EPA/DHA
    • 1.2-1.8 g/d EPA, 0.6-0.9 g/d DHA
  • Anti-inflammatory effect
  • Antioxidant effect (reduced oxidative stress with sulphasalazine @ 4.5 g/day)
  • Most research in UC, but wild-caught fish in both is found to be helpful 
  • Omega HP has added lipase to enhance digestibility, filtered to remove heavy metals/toxins, high potency 
  • High intake of Omega 3’s foods are associated with CRP < 5
  • Sources: 
    • https://pubmed.ncbi.nlm.nih.gov/1553930/ 
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097150/ 
    • https://pubmed.ncbi.nlm.nih.gov/15822041/ 
    • https://pubmed.ncbi.nlm.nih.gov/1312317/ 
    • https://pubmed.ncbi.nlm.nih.gov/17443620/ 
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378570/ 

https://pubmed.ncbi.nlm.nih.gov/17443620/

⭐starring system criteria:

• Works well with medications
• Additional benefits
• Has evidence to support its benefit 
• Easy to incorporate into daily routine 
• Cost effective
• High Quality Brand
• Well-absorbed formulation